Radiesse Volumizing Dermal Filler patient in Phoenix, ArizonaAs of March 2015, RADIESSE® (+) was FDA approved to replace RADIESSE® Volumizing Filler. The difference is that RADIESSE® (+) comes pre-mixed with 0.3% powdered lidocaine. This difference provides a significantly more comfortable treatment experience with the same correction properties as before.

RADIESSE® (+) is manufactured by MERZ AESTHETICS and is an opaque dermal filler that contains calcium-based microspheres suspended in a water-based gel carrier. As it contains no animal proteins, it does not require allergy pre-testing. This product works in two ways. The gel carrier gives an immediate correction. The calcium-based microspheres act as a scaffold, stimulating your body to produce its own natural collagen. Over time, the gel carrier is absorbed and the calcium-based microspheres are metabolized by your body, leaving behind the newly created collagen. A treatment with RADIESSE® (+) may result in a correction lasting a year or longer.

Willo MediSpa

201 E. Monterey Way
Phoenix, AZ85012

(602) 296-4477

RADIESSE® (+) can be used in multiple areas. It can be injected deeply to lift and augment the cheeks, temples, chin and pre-jowl area. It can be injected more superficially for nasolabial folds, marionette lines and chin creases.

Willo MediSpa in Central Phoenix serving Arcadia provides Radiesse injections to patientsIn February 2015, RADIESSE® (+) received FDA Panel Approval for Hand Augmentation. It is an ideal product to inject under the skin of the dorsal surface of the hands to give them a more youthful appearance. The FDA approved treatment with RADIESSE® Volumizing Filler for Facial Lipoatrophy associated with HIV. This topic will be discussed in its own section.

RADIESSE® (+) has the same precautions as other dermal fillers with a three exceptions. The calcium-based microspheres are visible on CT scans and may be visible in standard plain radiography. It is advised to tell your treating physician or radiologist that you have had RADIESSE® (+) injected in your face before any radiological studies are preformed. The second precaution is that RADIESSE® (+) has been known to activate herpes simplex in patients with a history of herpes simplex. It is not recommended to pre-treat for this condition, but treatment should be started if any symptoms arise after an injection procedure. The third precaution is that RADIESSE® (+) should not be injected around the eyes or in the lips as the formation of nodules may occur in these areas.

Radiesse® Treatment for Hands | Willo MediSpa

The most common adverse reactions to RADIESSE® (+) include swelling, allergic reaction, infection and local tissue damage or necrosis. Swelling for a few days after a treatment is very common and usually resolves within a few days with periodic icing. However, it has been reported to start up to 3 weeks later. This delayed swelling may require treatment with antibiotics, anti-histamines and steroids. An allergic reaction to the water-based gel carrier has been identified which may require treatment with anti-histamines and steroids. Infection is most commonly associated with pain, redness, hardened areas and pustules. The onset of infection has been reported up to 2 months after a treatment and would require antibiotic therapy. Necrosis of skin tissue would be the most problematic adverse reaction. It could be caused by an occlusion of the blood supply to the skin and present as blanching, tingling, bruising, redness or swelling of the treated area. RADIESSE® (+) cannot be dissolved with an enzyme unlike hyaluronic acid dermal fillers. Treatment for suspected necrosis includes nitroglycerin ointment for vasodilation of occluded blood vessels, pain management, antibiotics, non-steroidal wound ointments and warm compresses.


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